How Long After Taking Sumatriptan Can I Drink Alcohol?

Can I drink alcohol while taking sumatriptan? Alcohol does not affect how sumatriptan works.

Contents

1 How long does sumatriptan stay in your system?
2 How long to wait after taking sumatriptan?
- 2.1 What not to do while taking sumatriptan?
  - 2.1.1 Can you drink after taking migraine medicine?
3 Why can you only get 9 sumatriptan a month?
4 Why do I feel weird after taking sumatriptan?
5 Can I drink coffee with sumatriptan?
6 Can you sleep after taking sumatriptan?
- 6.1 Can you smoke while taking sumatriptan?
7 Can I drink an energy drink with sumatriptan?
- 7.1 Is sumatriptan hard on the liver?
- 7.2 Is sumatriptan hard on the heart?
  - 7.2.1 Can I drink alcohol after a migraine?
8 Can you drink alcohol after taking headache pills?
- 8.1 How long after taking headache medicine can you drink alcohol?
  - 8.1.1 Can I take sumatriptan 2 days in a row?
- 8.2 Is it bad to take sumatriptan 3 days in a row?
9 Is 100 mg of sumatriptan a lot?
10 Why does sumatriptan make me feel good?
11 Can I take sumatriptan with paracetamol?
- - 11.0.1 Does sumatriptan affect memory?
12 Is it bad to take sumatriptan 3 days in a row?
13 Can I take sumatriptan 2 days in a row?
- - 13.0.1 Why can you only take sumatriptan twice a week?
14 Can you sleep after taking sumatriptan?

How long does sumatriptan stay in your system?

– It’s not known if Imitrex is safe to take while breastfeeding. This drug hasn’t been studied in women who are breastfeeding. Imitrex may pass into breast milk, but it’s not known if this can affect a breastfed child. If you’re breastfeeding, talk with your doctor about whether Imitrex is right for you.

How long to wait after taking sumatriptan?

Proper Use – Drug information provided by: Merative, Micromedex ® Do not use this medicine for a headache that is different from your usual migraines. Talk to your doctor about what to do for regular headaches. To relieve your migraine as soon as possible, use this medicine as soon as the headache pain begins.

Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using sumatriptan. Ask your doctor ahead of time about any other medicine you might take if sumatriptan does not work. After you use the other medicine, check with your doctor as soon as possible.

Headaches that are not relieved by sumatriptan are sometimes caused by conditions that need other treatment. If you feel much better after a dose of sumatriptan, but your headache comes back or gets worse after a while, wait at least 2 hours before taking another dose.

However, use this medicine only as directed by your doctor.
Do not use more of it, and do not use it more often, than directed.
Using too much sumatriptan may increase the chance of side effects.
Do not take more than 200 mg in 24 hours.
Swallow the tablet whole with water or other liquids.
Do not crush, break, or chew it.

You may take the tablet with or without food. This medicine comes with a patient information leaflet. Read and follow the instructions carefully. Ask your doctor if you have any questions.

What not to do while taking sumatriptan?

Precautions – It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to use it. Check with your doctor if you used this medicine and it did not work.

Also, check with your doctor if your migraine headaches are worse or if they are occurring more often since you started using this medicine.
You should not use this medicine if you have used an MAO inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) within the past 2 weeks.
Do not use this medicine if you have taken other triptan migraine medicines or ergot-type medicines within the past 24 hours.

Some examples of triptan medicines are almotriptan (Axert®), eletriptan (Relpax®), naratriptan (Amerge®), or zolmitriptan (Zomig®). Some examples of ergot-type medicines are dihydroergotamine (D.H.E.45®, Migranal®), ergotamine (Bellergal®, Cafergot®, Ergomar®, Wigraine®), or methysergide (Sansert®).

This medicine may cause problems if you have heart disease.
If your doctor thinks you might have a problem with this medicine, he or she may want you to take your first dose in the doctor’s office or clinic.
This medicine may increase your risk of having abnormal heart rhythm, heart attack, angina, or stroke.

This is more likely to occur if you or a family member already has heart disease, if you have diabetes, high blood pressure, high cholesterol, or if you smoke. Call your doctor right away if you have any symptoms of a heart problem, such as chest pain or discomfort, an uneven heartbeat, nausea or vomiting, pain or discomfort in the shoulders, arms, jaw, back, or neck, shortness of breath, or sweating.

Call your doctor right away if you have any symptoms of a stroke, such as confusion, difficulty with speaking, double vision, headaches, an inability to move the arms, legs, or facial muscles, an inability to speak, or slow speech. Check with your doctor right away if you have chest discomfort, jaw or neck tightness after using this medicine.

Also, tell your doctor if you have sudden or severe abdominal or stomach pain or bloody diarrhea after using this medicine. Check with your doctor immediately if blurred vision, difficulty in reading, or any other change in vision occurs during or after your treatment.

Your eyes may need to be checked by an ophthalmologist (eye doctor). Using sumatriptan alone or in combination with other migraine medicines for 10 or more days per month may lead to worsening of headache. You may keep a headache diary to record your headache frequency and drug use. Make sure your doctor knows about all the other medicines you are using.

Sumatriptan may cause a serious condition called serotonin syndrome when taken with some medicines. This especially includes medicines used to treat depression, such as citalopram, duloxetine, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, venlafaxine, Celexa®, Cymbalta®, Effexor®, Lexapro®, Luvox®, Paxil®, Prozac®, Sarafem®, Symbyax®, or Zoloft®.

Check with your doctor right away if you have agitation, confusion, diarrhea, excitement while talking that is not normal, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, trembling or shaking that you cannot control, or twitching.
These could be symptoms of serotonin syndrome.

This medicine may cause a serious type of allergic reaction called anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes.

If these effects occur, get emergency help at once.
Drinking alcoholic beverages can make headaches worse or cause new headaches to occur.
People who suffer from severe headaches should probably avoid alcoholic beverages, especially during a headache.
Some people feel dizzy or drowsy during or after a migraine, or using sumatriptan to relieve a migraine.

As long as you are feeling dizzy or drowsy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Can you drink after taking migraine medicine?

Timing is important – Alcohol and medicines can interact harmfully even if they are not taken at the same time. Mixing alcohol and medicines puts you at risk for dangerous reactions. Protect yourself by avoiding alcohol if you are taking a medication and don’t know its effect.

Commonly Used Medicines (Both Prescription and Over-the-Counter) That Interact With Alcohol


Symptom/Disorders	Medication (Brand name)	Medication (Generic name)	Some possible reactions with alcohol
Allergies/Colds/Flu	Alavert®	Loratadine	Drowsiness, dizziness; increased risk for overdose
Atarax®	Hydroxyzine
Benadryl®	Diphenhydramine
Clarinex®	Desloratadine
Claritin®, Claritin-D®	Loratadine
Dimetapp® Cold &Allergy	Brompheniramine
Sudafed® Sinus & Allergy	Chlorpheniramine
Triaminic® Cold & Allergy	Chlorpheniramine
Tylenol® Allergy Sinus	Chlorpheniramine
Tylenol® Cold & Flu	Chlorpheniramine
Zyrtec®	Cetirizine
Angina (chest pain), coronary heart disease	Isordil®	Isosorbide Nitroglycerin	Rapid heartbeat, sudden changes in blood pressure, dizziness, fainting
Anxiety and epilepsy	Ativan®	Lorazepam	Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
BuSpar®	Buspirone
Klonopin®	Clonazepam
Librium®	Chlordiazepoxide
Paxil®	Paroxetine
Valium®	Diazepam
Xanax®	Alprazolam
Herbal preparations (Kava Kava)		Liver damage, drowsiness
Arthritis	Celebrex®	Celecoxib	Ulcers, stomach bleeding, liver damage
Naprosyn®	Naproxen
Voltaren®	Diclofenac
Attention and concentration (Attention deficit/hyperactivity disorder)	Adderall®	Amphetamine/dextro-amphetamine	Dizziness, drowsiness, impaired concentration (methylphenidate, dexmethylphenidate); possible increased risk for heart problems (amphetamine, dextroamphetamine, lisdexamfetamine); liver damage (atomoxetine)
Concerta®, Ritalin®	Methylphenidate
Dexedrine®	Dextroamphetamine
Focalin®	Dexmethylphenidate
Strattera®	Atomoxetine
Vyvanse®	Lisdexamfetamine
Blood clots	Coumadin®	Warfarin	Occasional drinking may lead to internal bleeding; heavier drinking also may cause bleeding or may have the opposite effect, resulting in possible blood clots, strokes, or heart attacks
Cough	Delsym®, Robitussin Cough®	Dextromethorpan	Drowsiness, dizziness; increased risk for overdose
Robitussin A–C®	Guaifenesin + codeine
Depression	Abilify®	Aripriprazone	Drowsiness, dizziness; increased risk for overdose; increased feelings of depression or hopelessness (all medications); impaired motor control (quetiapine, mirtazapine); increased alcohol effect (bupropion); liver damage (duloxetine) Monoamine oxidase inhibitors (MAOIs), such as tranylcypromine and phenelzine, when combined with alcohol, may result in serious heart-related side effects. Risk for dangerously high blood pressure is increased when MAOIs are mixed with tyramine, a byproduct found in beer and red wine
Anafranil®	Clomipramine
Celexa®	Citalopram
Clozaril®	Clozapine
Cymbalta®	Duloxetine
Desyrel®	Trazodone
Effexor®	Venlafaxine
Elavil®	Amitriptyline
Geodon®	Ziprasidone
Invega®	Paliperidone
Lexapro®	Escitalopram
Luvox®	Fluvoxamine
Nardil®	Phenelzine
Norpramin®	Desipramine
Pamate®	Tranylcypromine
Paxil®	Paroxetine
Pristiq®	Desevenlafaxine
Prozac®	Fluoxetine
Remeron®	Mirtazapine
Risperdal®	Risperidone
Seroquel®	Quetiapine
Serzone®	Nefazodone
Symbyax®	Fluoxetine/Olanzapine
Wellbutrin®	Bupropion
Zoloft®	Sertraline
Zyprexa®	Olanzapine
Herbal preparations (St. John’s Wort)
Diabetes	Diabinese®	Chlorpropamide	Abnormally low blood sugar levels, flushing reaction (nausea, vomiting, headache, rapid heartbeat, sudden changes in blood pressure); symptoms of nausea and weakness may occur (metformin)
Glucotrol®	Glipizide
Glucophage®	Metformin
Glynase®, DiaBeta®, Micronase®	Glyburide
Orinase®	Tolbutamide
Tolinase®	Tolazamide
Enlarged prostate	Cardura®	Doxazosin	Dizziness, light headedness, fainting
Flomax®	Tamsulosin
Hytrin®	Terazosin
Minipress®	Prazosin
Heartburn, indigestion, sour stomach	Axid®	Nizatidine	Rapid heartbeat; increased alcohol effect; sudden changes in blood pressure (metoclopramide)
Reglan®	Metoclopramide
Tagamet®	Cimetidine
Zantac®	Ranitidine
High blood pressure	Accupril®	Quinapril	Dizziness, fainting, drowsiness; heart problems such as changes in the heart’s regular heartbeat (arrhythmia)
Calan®	Verapamil
Capozide®	Hydrochlorothiazide
Cardura®	Doxazosin
Catapres®	Clonidine
Cozaar®	Losartan
Hytrin®	Terazosin
Lopressor® HCT	Hydrochlorothiazide
Lotensin®	Benzapril
Minipress®	Prazosin
Norvasc®	Amlodipine mesylate
Prinivil®, Zestril®	Lisinopril
Vaseretic®	Enalapril
High cholesterol	Advicor®	Lovastatin + Niacin	Liver damage (all medications); increased flushing and itching (niacin), increased stomach bleeding (pravastatin + aspirin)
Altocor®	Lovastatin
Crestor®	Rosuvastatin
Lipitor®	Atorvastatin
Mevacor®	Lovastatin
Niaspan®	Niacin
Pravachol®	Pravastatin
Pravigard™	Pravastatin + Aspirin
Vytorin™	Ezetimibe + Simvastatin
Zocor®	Simvastatin
Infections	Acrodantin®	Nitrofurantoin	Fast heartbeat, sudden changes in blood pressure; stomach pain, upset stomach, vomiting, headache, or flushing or redness of the face; liver damage (isoniazid, ketoconazole)
Flagyl®	Metronidazole
Grisactin®	Griseofulvin
Nizoral®	Ketoconazole
Nydrazid®	Isoniazid
Seromycin®	Cycloserine
Tindamax®	Tinidazole
Zithromax®	Azithromycin
Mood stabilizers	Depakene®, Depakote®	Valproic acid	Drowsiness, dizziness; tremors; increased risk for side effects, such as restlessness, impaired motor control; loss of appetite; stomach upset; irregular bowel movement; joint or muscle pain; depression; liver damage (valproic acid)
Eskalith®, Eskalith®CR, Lithobid	Lithium
Muscle pain	Flexeril®	Cyclobenzaprine	Drowsiness, dizziness; increased risk of seizures; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Soma®	Carisoprodol
Nausea, motion sickness	Antivert®	Meclizine	Drowsiness, dizziness; increased risk for overdose
Dramamine®	Dimenhydrinate
Phenergan®	Promethazine
Pain (such as muscle ache, minor arthritis pain), fever, inflammation	Advil®	Ibuprofen	Stomach upset, bleeding and ulcers; liver damage (acetaminophen); rapid heartbeat
Aleve®	Naproxen
Excedrin®	Aspirin, Acetaminophen
Motrin®	Ibuprofen
Tylenol®	Acetaminophen
Seizures	Dilantin®	Phenytoin	Drowsiness, dizziness; increased risk of seizures (levetiracetam, phenytoin); unusual behavior and changes in mental health (such as thoughts of suicide) (topiramate)
Horizant®, Neurontin®	Gabapentin
Keppra®	Levetiracetam
Klonopin®	Clonazepam
	Phenobarbital
Lamictal®	Lamotrigine
Lyrica®	Pregabalin
Tegretol®	Carbamazepine
Topamax®	Topiramate
Trileptal®	Oxcarbazepine
	Barbiturates
Severe pain from injury, postsurgical care, oral surgery, migraines	Darvocet–N®	Propoxyphene	Drowsiness, dizziness; increased risk for overdose; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Demerol®	Merepidine
Fiorinal® with codeine	Butalbital + codeine
Percocet®	Oxycodone
Vicodin®	Hydrocodone
Sleep problems	Ambien®	Zolpidem	Drowsiness, sleepiness, dizziness; slowed or difficulty breathing; impaired motor control; unusual behavior; memory problems
Lunesta™	Eszopiclone
Prosom™	Estazolam
Restoril®	Temazepam
Sominex®	Diphenhydramine
Unisom®	Doxylamine
Herbal preparations (chamomile, valerian, lavender)		Increased drowsiness

Why can you only get 9 sumatriptan a month?

Experts Answer Your Questions: New Warnings on Imitrex? | National Headache Foundation Q. I’ve been a National Headache Foundation subscriber for many years and a sufferer for over 40 years. When Imitrex (sumatriptan) was available it was a miracle for me.

I have taken Imitrex for many years, usually having my physician prescribe three packages (27 pills) for a 3 month’s supply (mail order).
Now my physician has limited me to only one package (9 pills) for 3 months, stating that there have been new warnings about sumatriptan use and that patient use of it needs to be closely monitored.

I have always been careful not to exceed two doses in a 24-hour period, but often my migraines come in clusters and I might need to take, 6 or more pills in one week, so the 9 pills will never last 3 months. Are there new warnings on Imitrex or do you think this is an insurance problem? A.

It is unfortunate that many migraine sufferers are limited on how many triptans pills (i.e.-Imitrex) they may receive. This may lead to increased days of disability and unnecessary anxiety. I am not sure if your physician or your prescription plan is limiting you but it is more likely your prescription plan.

Many prescription plans limit relatively expensive medications. Most triptans pills are about $20 per pill. The medication package insert for Imitrex (and many triptans) states “the safety of treating an average of more than 4 headaches in a 30-day period has not been established.” This statement does not mean they are not safe if used more frequently and many headache specialists, including myself, feel comfortable prescribing them up to 2 days per week in healthy patients.

However, some prescription plans use this statement to mean a maximum of 4 treatment days per month with an average of 1 ½ doses per headache, thus limiting coverage to 6 pills per month. Since Imitrex comes in packages of 9, you are allowed 9 per month. Ask your prescription plan if they have an appeals process which will allow more.

Loretta Mueller D.O. University Headache Center Stratford, NJ

Why do I feel weird after taking sumatriptan?

Also, check with your doctor if your migraine headaches are worse or if they are occurring more often since you started using this medicine. You should not use this medicine if you have used an MAO inhibitor (MAOI) such as phenelzine (Nardil®) or tranylcypromine (Parnate®) within the past 2 weeks. Do not use this medicine if you have taken other triptan migraine medicines or ergot-type medicines within the past 24 hours.

This medicine may cause problems if you have heart disease. If your doctor thinks you might have a problem with this medicine, he or she may want you to take your first dose in the doctor’s office or clinic. This medicine may increase your risk of having abnormal heart rhythm, heart attack, angina, or stroke.

Call your doctor right away if you have any symptoms of a stroke, such as confusion, difficulty with speaking, double vision, headaches, an inability to move the arms, legs, or facial muscles, an inability to speak, or slow speech.
Check with your doctor right away if you have chest discomfort, jaw or neck tightness after using this medicine.

Your eyes may need to be checked by an ophthalmologist (eye doctor).
Using sumatriptan alone or in combination with other migraine medicines for 10 or more days per month may lead to worsening of headache.
You may keep a headache diary to record your headache frequency and drug use.
Make sure your doctor knows about all the other medicines you are using.

Check with your doctor right away if you have agitation, confusion, diarrhea, excitement while talking that is not normal, fever, overactive reflexes, poor coordination, restlessness, shivering, sweating, trembling or shaking that you cannot control, or twitching. These could be symptoms of serotonin syndrome.

If these effects occur, get emergency help at once. Drinking alcoholic beverages can make headaches worse or cause new headaches to occur. People who suffer from severe headaches should probably avoid alcoholic beverages, especially during a headache. Some people feel dizzy or drowsy during or after a migraine, or using sumatriptan to relieve a migraine.

As long as you are feeling dizzy or drowsy, do not drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.

Can I drink coffee with sumatriptan?

DISCUSSION – In this study, levetiracetam (1–50 mg/kg; per os) exerted significant dose-dependent reduction of nociceptive behavior induced by injection of formalin into the orofacial area in rats. Because it did not influence motor performance in a dose of 200 mg/kg (per os), 8 the effect of levetiracetam in the orofacial formalin test can be attributed to its antinociceptive action.

In contrast, we showed that the highest dose of levetiracetam (50 mg/kg; per os) was without any effect in the paw formalin test, under the same experimental conditions. An absence of effect of levetiracetam (100–600 mg/kg; intraperitoneally) in the paw formalin test was also reported by Munro et al., 34 in a different strain of rats (Sprague-Dawley).

The highly effective and potent action of levetiracetam in the orofacial formalin test and the absence of its effect in the paw formalin test could indicate that the trigeminal area is particularly sensitive to its antinociceptive action. The early phase of the formalin test seems to be caused predominantly by direct chemical stimulation of nociceptors, while the late phase appears to be dependent on the combination of peripheral inflammation and functional changes in central pain processing.25, 35 Because levetiracetam produced antinociception in both phases of the orofacial formalin test, it could be suggested that it can reduce pain in the trigeminal region that involves nociception, inflammation, and/or central sensitization.

Sumatriptan (0.5–5 mg/kg; per os) reduced nociceptive behavior in the orofacial formalin test in doses that do not alter rotarod performance. In the paw formalin test, sumatriptan (5 mg/kg; per os) did not exert significant antinociception. Previously, the effects of sumatriptan were examined in rats and mice paw formalin tests, and the studies revealed variable results ranging from an absence of the effect after systemic administration to significant antinociception after intrathecal and local peripheral administration.36, 37 In the present study, comparable efficacy and similar potency of levetiracetam and sumatriptan in the orofacial formalin test have been observed.

Although the extrapolation of findings from animals to humans is limited, this could indicate that levetiracetam may have comparable effects as sumatriptan for pain treatment in the trigeminal region in humans. Caffeine 7.5–100 mg/kg (per os) significantly reduced formalin-induced face rubbing in the second phase of the orofacial formalin test; the highest tested dose (100 mg/kg) produced a modest effect of 51.5% AN.

In the paw formalin test, caffeine (100 mg/kg) produced a significant decrease of nociceptive behavior in both phases, with a magnitude of 60.1% and 52.3% for the first and the second phases of the test, respectively.
Because caffeine 100 mg/kg did not influence the rotarod performance, its effects in the formalin tests were antinociceptive.

Earlier studies also demonstrated a significant dose-dependent antinociception of caffeine (2.5–10 mg/kg and 35–75 mg/kg; intraperitoneally) in the paw formalin test, in a different strain of rats (Sprague-Dawley).38, 39 In contrast to levetiracetam and sumatriptan, it seems that the site of formalin injection is not important for the action of caffeine in this model.

Caffeine, in doses that were subeffective after individual administration (1–7.5 mg/kg; per os), caused significant reduction of antinociceptive effects of levetiracetam in the orofacial formalin test. We have previously examined the interaction between systemic levetiracetam and caffeine in a carrageenan-induced inflammatory hyperalgesia model.

Applied in lower doses, caffeine (1–5 mg/kg; intraperitoneally) significantly and dose-dependently decreased the antihyperalgesic effect of levetiracetam, whereas a higher caffeine dose (10 mg/kg; intraperitoneally) enhanced its effects.17, 40 Sawynok 21, 22 suggested that the effects of caffeine on analgesic effects of other agents depend on its dose; low caffeine doses (usually up to 10 mg/kg) may exert inhibitory effects.

Low caffeine doses also inhibited antihyperalgesic effects of oxcarbazepine and carbamazepine in an inflammatory pain model in rats 27 and antinociceptive effects of oxcarbazepine in the formalin test in mice.41 Our present finding might indicate that adenosine A 1 receptors are involved in the antinociception of levetiracetam in this pain model because A 1 receptor agonists produced antinociception in the formalin test 42, 43 and caffeine acts as a nonselective adenosine receptor antagonist.21 We previously detected that a selective adenosine A 1 receptor antagonist reduced the antihyperalgesic effects of levetiracetam after both systemic and local peripheral administration, suggesting that A 1 receptors are involved in its action in a somatic inflammatory pain model.7, 44 However, experiments using selective A 1 antagonist are needed to confirm the involvement of A 1 receptors in the action of levetiracetam in this model of trigeminal pain.

Caffeine also reduced the antinociceptive effects of sumatriptan. Triptans activate 5-HT 1B/1D receptors at central sites to reduce the transmission of pain signals and to activate descending pain-inhibitory pathways.45–47 The adenosine pain inhibitory system could be involved in the antinociception of sumatriptan because 5-HT 1 receptor activation enhances the release of adenosine in the spinal cord 48 and methylxanthine adenosine receptor antagonist inhibits antinociception induced by intrathecal selective 5-HT 1 receptor agonists.49 The inhibitory effect of caffeine on sumatriptan’s antinociception observed in our study might be explained by its blocking effects on the actions of adenosine released subsequent to 5-HT 1 receptor activation.

The doses of caffeine (1–7.5 mg/kg) that exhibited inhibitory effects on antinociception produced by levetiracetam and sumatriptan seem to correlate with human doses ingested in caffeine-containing beverages/foods. The caffeine content in a cup of coffee ranges from 100 to 500 mg, in energy drinks 100 to 300 mg, in frozen desserts 50 to 80 mg, and in tea 25 to 50 mg.21, 50 Those amounts correspond to human intake doses of about 0.4 to 7.1 mg/kg.

The marked inhibition of sumatriptan/levetiracetam’s analgesia by caffeine observed here raises the possibility that dietary caffeine intake might interfere with analgesic efficacy of sumatriptan/levetiracetam in clinical settings. The combination of levetiracetam and sumatriptan resulted in an additive antinociceptive interaction in the inflammatory phase of the test.

Additivity is usually ascribed to the activation of a common mechanism mediating the observed effect.51, 52 Although levetiracetam and sumatriptan belong to distinct pharmacologic classes, it is possible that they have a common mechanism(s) of antinociceptive action in this pain model.
We have previously demonstrated that 5-HT 1B/1D and A 1 receptors at least partly mediate levetiracetam’s antihyperalgesia in a rat model of inflammation.7, 44 As discussed above, sumatriptan stimulates 5-HT 1B/1D receptors and may possibly cause the release of adenosine.

We can suppose that the activation of the adenosine pain inhibitory system might have a particularly important role in the action of both drugs in this phase of the test because caffeine caused dose-dependent inhibition of their antinociceptive actions, which was complete with the highest caffeine dose used in our study.

But, further investigation is needed to examine this possibility.
Although additivity means that the dose of each component in combination could be 2-fold reduced (and produce the same analgesia as each component in a full dose alone), this dose reduction could still be clinically meaningful because it could reduce the dose-dependent, drug-specific adverse effects.

Preclinical examination of the side effects of a levetiracetam–sumatriptan combination may have less predictive value than the examination of its analgesic effects. However, the highest tested dose of a levetiracetam–sumatriptan combination revealed no significant effect in the rotarod test, indicating that there is no addition/enhancement of their possible effects on motor coordination or sedation in rats.

In humans, the addition/enhancement of the side effects of levetiracetam and sumatriptan seems less likely because their side effect profiles appear to be mostly different.53, 54 The efficacy and tolerability of a levetiracetam–sumatriptan combination should be verified in clinical studies.
In conclusion, our results indicate that levetiracetam may be useful for treatment of pain in the trigeminal region.

Dietary caffeine might decrease the effects of levetiracetam and sumatriptan; this needs to be considered in clinical settings. The effectiveness and adverse effects of a levetiracetam–sumatriptan combination should be examined in patients with trigeminal pain.

Can you sleep after taking sumatriptan?

Sumatriptan – for migraine and cluster headaches – Imigran

Use sumatriptan as soon as the migraine headache or cluster headache develops. It can make you feel tired or sleepy. If this happens, do not drive and do not use tools or machines. Your chest may feel tight or ‘heavy’ after taking sumatriptan. These sensations do not usually last for long, but if they continue or become intense, do not take any more sumatriptan and let your doctor know as soon as possible. Other side-effects may occur, but they are generally mild and do not last for long.

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Type of medicine 5HT 1 -receptor agonist (also known as a ‘triptan’) Used for Treatment of acute migraine attacks and cluster headaches Also called Imigran®; Migraitan® Available as Tablets, dispersible tablets, nasal spray and injection

In people with, it is thought that some chemicals in the brain increase in activity and as a result parts of the brain then send out confused signals which result in the symptoms of headache and sickness. Why people with migraine should develop these chemical changes is not clear.

Many migraine attacks occur for no apparent reason, but for some people there may be things which trigger an attack, like certain foods or drinks.
Consist of attacks of severe one-sided pain in the head.
Typically, a number of attacks will occur over several weeks and then pass.
It may then be weeks, months or years until the next cluster of headaches develops.

Sumatriptan belongs to a class of medicines known as 5HT 1 -receptor agonists. They are also known simply as triptans. Triptans work by stimulating the receptors of a natural substance in the brain, called serotonin (or 5HT). This and cluster headaches.

There are two strengths of sumatriptan tablet available (50 mg and 100 mg), one strength of injection (6 mg/0.5 ml) and one strength of nasal spray (10 mg/actuation). The injection is usually prescribed for people with cluster headaches, whereas the injection, spray or tablets may be prescribed for people with migraines.

Sumatriptan 50 mg tablets can be purchased from pharmacies for the treatment of migraine headache. The pharmacist will need to check that the medicine is suitable for you to take. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.

If you are aged over 65 years or under 18 years.If you are pregnant or breastfeeding.If you have a heart condition such as angina, or if you have had a heart attack.If you have high blood pressure (hypertension).If you have circulation problems.If you have any problems with the way your liver works or with the way your kidneys work.If you have ever had a stroke or a transient ischaemic attack (this is also referred to as a TIA, or ‘mini-stroke’).If you have ever had a fit (seizure).If you have ever had an allergic reaction to a medicine. It is particularly important that you tell your doctor if you have had a bad reaction to a sulfonamide antibiotic (such as co-trimoxazole or sulfadiazine).If you are taking or using any other medicines. This includes any medicines you are taking which are available to buy without a prescription, as well as herbal and complementary medicines.

Before you start this treatment, read the manufacturer’s printed information leaflet from inside the pack. It will give you more information about sumatriptan and a full list of the side-effects which you may experience from taking it. It will also provide you with a step-by-step guide and diagrams to show you how to use the preparation you have been supplied with. If you are still unsure what to do, ask your pharmacist for further advice.Your dose will be on the label of the pack. Take sumatriptan exactly as your doctor tells you to.If you are taking tablets : take one (50 mg or 100 mg) tablet with a drink of water, as soon as the headache phase develops. You can take Imigran Radis® tablets stirred into a small amount of water. If your migraine at first improves but then comes back, you may take a further dose, providing it is at least two hours after the initial dose. If the first tablet has no effect, do not try a second dose for the same attack, as it is unlikely to work.If you are using the injection : inject one dose as soon as the headache develops. If your headache at first improves but then comes back, you may use one further dose, providing it is at least one hour after the initial dose. Do not use more than two doses in 24 hours. If the first dose has no effect, do not try a second dose for the same attack, as it is unlikely to work. The needle shield may contain natural latex rubber.If you using the nasal spray : use the spray as soon as the headache phase develops. If your migraine at first improves but then comes back, you can use the spray again providing it is at least two hours after your first dose. Do not use the spray more than twice in 24 hours. If the first spray has no effect, do not try a second dose for the same attack, as it is unlikely to work.

Sumatriptan is used to treat headache pain during a migraine attack, not to stop the pain from coming on. You should wait until the migraine symptoms start to develop, rather than taking it when you feel that a migraine may be developing.Do not take other migraine treatments (such as other triptans or ergotamine) at the same time as sumatriptan.Some people may benefit from taking a non-steroidal anti-inflammatory painkiller (such as naproxen) in addition to sumatriptan. Your doctor will advise you about this if it is recommended for you.If you find that sumatriptan does not relieve your migraine, make an appointment to discuss this with your doctor, as an alternative medicine may be more effective for you.It may help to keep a migraine diary. Note down when and where each migraine attack started, what you were doing, and what you had eaten that day. A pattern may emerge and it may be possible for you to avoid some of the things that trigger your migraine attacks.Sumatriptan is used to treat migraine attacks once the pain has started, but there are other medicines available that may help to reduce the number of migraine attacks. If you have migraines frequently, discuss this with your doctor.Some people who get frequent migraine attacks are in fact getting medication-induced headache. Medication-induced headache (also called medication-overuse headache) is caused by taking painkillers or triptans too often. If you use sumatriptan or painkillers on more than two days a week on a regular basis, you may be at risk of this. You should talk with your doctor if you suspect it.

Sumatriptan is usually given by injection for cluster headache, as it provides pain relief in about 5-15 minutes in most people.You will be shown how to use the injection. You should use it as soon as a headache occurs. The adult dose is one 6 mg injection for each headache. If you get more than one headache a day, the maximum dose you can have in 24 hours is two 6 mg injections. You must leave at least one hour between the two injections.You may also be prescribed another medicine to try to prevent the headaches from occurring. Preventative treatment is often taken over the period of the cluster headaches and is then stopped, although some treatments are taken longer-term.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with sumatriptan. You will find a full list in the manufacturer’s information leaflet supplied with your medicine.

Common sumatriptan side-effects	What can I do if I experience this?
Feeling dizzy, sleepy, or tired	If this happens, do not drive and do not use tools or machines
Feeling sick (nausea) or being sick (vomiting)	Stick to simple foods
Feelings ot tightness or heaviness, particularly in the throat or chest	If the pain is intense, do not take any further doses and speak with your doctor about it as soon as possible
Tingling feelings, feeling flushed, feeling warm or cold, aches and pains, increased blood pressure, feeling short of breath	If any of these become troublesome, speak with your doctor
Unpleasant or bitter taste (if using the nasal spray), and injection site reactions (if using the injection)	These should soon pass

If you experience any other symptoms that you think may be due to the medicine, speak with your doctor or pharmacist for advice.

Keep all medicines out of the reach and sight of children.Store in a cool, dry place, away from direct heat and light.

Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty. This medicine is for you. Never give it to other people even if their condition appears to be the same as yours. If you buy any medicines, check with a pharmacist that they are suitable to take with your other medicines. If you are having an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking. Do not keep out-of-date or unwanted medicines. Take them to your local pharmacy which will dispose of them for you. If you have any questions about this medicine, ask your pharmacist.

Sumatriptan – for migraine and cluster headaches – Imigran

Can you smoke while taking sumatriptan?

Notes for Consumers: Do not smoke or use tobacco products while taking this medication. Smoking while taking this medication increases the risk for stomach bleeding.

Can I drink an energy drink with sumatriptan?

Interactions between your drugs – Using SUMAtriptan together with ergotamine is not recommended. Combining these medications may have additive effects and cause excessive narrowing of blood vessels in the body. This can reduce blood flow to vital organs and increase the risk of rare but serious side effects such as high blood pressure, heart attack, stroke, and gangrene (death of tissues, usually in the arm or leg, that may require surgical amputation).

You should seek immediate medical attention if you experience severe abdominal pain, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of fingers or toes, pale or cold skin, chest pain or tightness, irregular heartbeat, severe headache, shortness of breath, blurred vision, confusion, and/or slurred speech during treatment with these medications.

Do not take larger doses or use the drug more frequently than prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor. Switch to professional interaction data

Is sumatriptan hard on the liver?

Special considerations – If you have mild or moderate liver disease, you should not take more than 50 mg of sumatriptan in a single dose. If you have severe liver disease, you should not use sumatriptan at all. Disclaimer: Our goal is to provide you with the most relevant and current information.

Is sumatriptan hard on the heart?

If you have any medical questions or concerns, please talk to your healthcare provider. The articles on Health Guide are underpinned by peer-reviewed research and information drawn from medical societies and governmental agencies. However, they are not a substitute for professional medical advice, diagnosis, or treatment.

Sumatriptan (brand name Imitrex) is a drug commonly prescribed for moderate to severe migraines and cluster headaches ( Smith, 2020 ).
If this is you, you’re looking for effective and safe pain relief, and sumatriptan may help you get back to your usual self.
Sumatriptan is effective and generally well-tolerated.

Research shows that serious side effects are relatively rare ( Perry, 1998 ). There are some patients for whom sumatriptan isn’t the right choice. Sumatriptan works in part by constricting blood vessels, so it may not be suitable for patients with the following conditions: CAD ( coronary artery disease ), TIA (transient ischemic attacks), hypertension, vasospasms, Prinzmetal angina, or history of heart attack or uncontrolled high blood pressure.

If you have any of these or related conditions, your healthcare provider may find you an alternative treatment for migraine ( FDA, 2013 ).
This article will walk you through the most important sumatriptan warnings and side effects and outline which patients would benefit from alternative treatments.
You should be able to take your medication safely and confidently, and we hope this article helps.

The drug information label is easier to understand if you know a little bit about sumatriptan and how it works. Sumatriptan is part of a group of drugs called triptans. They work like serotonin, a chemical that your body naturally produces to send signals between nerve cells.

Although researchers are still figuring out exactly why triptans work, they do know that they do two things: constrict the blood vessels in the brain and stop certain pain signals in the brain ( Ahn, 2005 ).
Reading the warnings section of any medication label can be alarming.
Here’s a run-down of the most important warnings on the sumatriptan label so you can better understand what they mean for you and your health and to avoid any adverse effects (FDA, 2013).

Some of the warnings on the label are there because sumatriptan works by constricting blood vessels (Ahn, 2005). The below warnings have to do with this effect of the drug (FDA, 2013):

Heart problems : Sumatriptan works by constricting blood vessels, so it may not be suitable for people with heart conditions. Sumatriptan can worsen coronary artery disease (ischemia) or provoke a heart attack (myocardial infarction) or Printzmetal’s angina (coronary artery vasospasm). It can also cause irregular heart rhythms.
Chest, neck, jaw, throat tightness : Sumatriptan, in some cases, has been shown to cause chest pain or a heavy feeling, pressure, or tightness in the chest, neck, jaw, or throat. Note that these can also be signs of a heart attack. If you experience these symptoms, especially if they are accompanied by nausea or vomiting, or if you have a history of coronary artery disease (heart attacks, angina), seek medical attention immediately.
High blood pressure : Constricting blood vessels can lead to a sudden increased blood pressure called hypertensive crisis, affecting organ function. Symptoms of a hypertensive crisis include a sudden pounding headache, nausea, vomiting, chest pain, dizziness, loss of consciousness, and difficulty breathing. If you experience any of these symptoms, seek immediate medical attention.
Ergotamines : you should not take sumatriptan within 24 hours of using ergotamines or other ergot-type medications. Together, these medications can cause excessive narrowing of the blood vessels, which can reduce blood flow to certain organs in the body ( Worthington, 2013 ).

Can I drink alcohol after a migraine?

Can I drink during a migraine attack? – Although it’s unlikely that you’d feel like it, it’s best not to drink any alcohol while you’re experiencing a migraine attack. Attacks can last for several hours or days after the headache stage eases. This is known as the postdrome stage and can make you feel very fatigued and ‘hungover’.

Can you drink alcohol after taking headache pills?

It depends on the type of painkiller. It is usually safe to drink a moderate amount of alcohol (no more than the daily guideline of alcohol units ) if you are taking a painkiller that can be bought over the counter such as paracetamol or ibuprofen; providing you get relevant advice.

How long after taking headache medicine can you drink alcohol?

Combining ibuprofen and alcohol can raise your risk for serious side effects, such as gastrointestinal (GI) bleeding and kidney or liver problems. It’s best to wait at least 10 hours after taking a dose of ibuprofen to drink alcohol.

Can I take sumatriptan 2 days in a row?

Triptans shouldn’t be used for more than 2 days per week or more than 10 days per month. If you need them more often than this, you may benefit from a daily preventative migraine medication. Taking triptans may raise the risk for certains heart problems.

Is it bad to take sumatriptan 3 days in a row?

– It may be possible for you to take sumatriptan oral tablets with certain other migraine medications. But you should only do so if your doctor recommends it. For example, if you often have migraine headaches, your doctor may prescribe preventive medication that you take every day.

divalproex (Depakote)erenumab ( Aimovig )fremanezumab ( Ajovy ) gabapentin (Neurontin) propranolol (Inderal) topiramate ( Topamax ) verapamil (Calan SR, Verelan)

If you have troublesome nausea with your migraine headaches, your doctor may also prescribe antinausea medication to take with sumatriptan oral tablets. Examples include:

metoclopramide (Reglan)ondansetron (Zofran) promethazine

Finally, if the recommended dose of sumatriptan does not relieve your symptoms, your doctor may recommend taking certain other pain-relieving medications. Examples include:

over-the-counter pain relievers, such as:

acetaminophen (Tylenol)

acetaminophen/aspirin/caffeine (Excedrin Migraine)

aspirin

ibuprofen (Advil, Motrin)

naproxen (Aleve)

prescription pain relievers, such as:

acetaminophen/caffeine/dihydrocodeine (Trezix)

acetaminophen/codeine (Tylenol with codeine)

diclofenac

ketorolac

tramadol

Note that taking pain relievers too often can lead to medication overuse headache, With this condition, you may have migraine-like headaches every day, or migraine headaches that happen more often than usual. If you need to use pain relievers for a headache 10 or more days per month, talk with your doctor.

Is 100 mg of sumatriptan a lot?

How much sumatriptan (or another triptan) is too much is not clear. The initial FDA-approved daily dose of oral sumatriptan (Imitrex) for the treatment of an acute migraine was up to three 100 mg tablets. Several years later the maximum daily dose was reduced to 2 100 mg tablets a day, to be taken at least 2 hours apart.

There was no scientific or safety reason for the reduction of the dose.
Two other triptans, rizatriptan (Maxalt) and frovatriptan (Frova) are still allowed to be taken three times a day.
The maximum dose of eletriptan (Relpax) is 2 40 mg tablets, however, in Europe it is 2 80 mg tablets.
Some doctors are very strict in adhering to these arbitrary limits.

Some patients will tell me that they always need to repeat the dose of a triptan 2 hours after the first dose. It makes sense to have them take a double dose at once and the results can be much better – the headache will go away and will not return. It is true that the higher the dose the more side effects you can expect.

In patients who are sensitive to drugs or weight less than 100 lbs, it is prudent to try half of the usually dose and in everyone else the standard dose should be used at first.
If the standard dose is not fully effective, another triptan can be tried, but if none provide sufficient relief and do not cause side effects I first recommend combining the standard dose of a triptan (100 mg of sumatriptan, 10 mg of rizatriptan, 40 mg of eletriptan, and so on) with an anti-inflammatory medication, such as Migralex (aspirin/magnesium), naproxen (Aleve), or ibuprofen (Advil).

Only if this combination also fails would I suggest doubling the standard dose of a triptan. What about the maximum dose of a triptan to be taken in a month? The initial studies of sumatriptan were conducted in patients who had 2 to 6 migraines a month and when the drug was approved by the FDA no monthly limit was imposed.

However, the manufacturer packaged sumatriptan tablets in a blister pack of 9 tablets. This became the unofficial limit, even though no studies were ever conducted to examine the safety and efficacy of frequent sumatriptan (or any other triptan) use. Many doctors, including headache specialists believe that taking any abortive medication, including triptans too frequently will make headaches worse (so-called medication overuse headaches).

We do have good scientific evidence showing that caffeine in fact can worsen headaches by causing caffeine withdrawal, or rebound headaches. People who drink large amounts of caffeine know that if they stop their caffeine intake they will develop a headache.

In patients prone to headaches, as little as 2 cups of coffee, tea, or soda can worsen their headaches. We also have some evidence that barbiturates, such as butalbital (Fioricet, Fiorinal, Esgic) and opioid analgesics, such as codeine, oxycodone (Percocet), hydrocodone (Vicodin) and other can cause worsening of headaches if taken more than once a week.

However, we have no evidence that triptans or NSAIDS, or non-steroidal anti-inflammatory drugs (Advil, Aleve, Motrin, Relafen, Voltaren, etc) cause worsening of headaches if taken frequently. Aspirin (such as in Migralex) in fact may prevent worsening of migraines.

I do discourage frequent use of triptans, which usually indicates poor control of migraines. Most patients with frequent migraine attacks are better off with preventive therapies, such as aerobic exercise, biofeedback, magnesium, CoQ10, Botox injections, or sometimes even preventive drugs. A common barrier to the frequent use of triptans is the insurance company.

Many insurers have been reducing their monthly coverage of triptans from 9 to 12 down to 4 or 6, while increasing co-pays. This is clearly done not out of any safety concerns, but to save money. With all of the above said, I do have about two dozen (out of thousands) patients who require very frequent or daily intake of triptans.

These patients have gone through many of the preventive treatments listed above, including Botox, and they are still having daily headaches, or what we call chronic migraines.
I usually try to have them stop triptans for several weeks to see if they improve with NSAIDs and prophylactic treatments, but most do not.

These patients have very good control of their migraines, have no side effects, and can function normally. I am concerned about the potential cardiac side effects of these drugs, which are well documented. If a patient has some risk factors for heart disease (post-menopausal, high cholesterol, hypertension, diabetes, smoking, obesity, family history, etc), a stress test should be obtained.

What prompted this post was an article in the latest issue of journal Headache, which reports on a 49-year-old woman with 18 years of chronic cluster headaches. Injectable sumatriptan is the only treatment approved for cluster headaches. This woman has been injecting herself with 6 mg of sumatriptan anywhere from 2 to 37 times every day (on average, 20 times) for 15 years.

She had no side effects or negative effects on her heart and there was no decline in the efficacy of sumatriptan over time. She failed several abortive and preventive medications. Other doctors have published articles describing patients taking triptans very frequently without loss of efficacy or side effects, but this patient has the most frequent and prolonged use ever reported.

Why does sumatriptan make me feel good?

pronounced as (soo ma trip’ tan) Sumatriptan is used to treat the symptoms of migraine headaches (severe, throbbing headaches that sometimes are accompanied by nausea or sensitivity to sound and light). Sumatriptan is in a class of medications called selective serotonin receptor agonists.

It works by narrowing blood vessels in the head, stopping pain signals from being sent to the brain, and blocking the release of certain natural substances that cause pain, nausea, and other symptoms of migraine.
Sumatriptan does not prevent migraine attacks or reduce the number of headaches you have.

Sumatriptan comes as a tablet to take by mouth. It is usually taken at the first sign of a migraine headache.If your symptoms improve after you take sumatriptan but return after 2 hours or longer, you may take a second tablet. However, if your symptoms do not improve after you take sumitriptan, do not take a second tablet without calling your doctor.

Your doctor will tell you the maximum number of tablets you may take in a 24-hour period.Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Take sumatriptan exactly as directed.
Do not take more or less of it or take it more often than prescribed by your doctor.

You may take your first dose of sumatriptan in a doctor’s office or other medical facility where you can be monitored for serious reactions. Call your doctor if your headaches do not get better or occur more frequently after taking sumatriptan. If you take sumatriptan more often or for longer than the recommended period of time, your headaches may get worse or may occur more frequently.

Can I take sumatriptan with paracetamol?

Sumatriptan with painkillers – If your first dose of sumatriptan doesn’t work to relieve your migraine, it’s fine to take a painkiller containing aspirin, paracetamol, or a non-steroidal anti-inflammatory drug (NSAID), such as ibuprofen.

Does sumatriptan affect memory?

Abstract – Lithium is a drug used for the treatment of bipolar disorder. It has several mechanisms of action, and recently it is shown that lithium can antagonize the 5-HT1B/1D serotonin receptors. Sumatriptan is a 5-HT1B/1D receptor agonist used for the treatment of cluster headaches and migraine which might cause memory impairment as a potential side effect. In this study, effects of lithium on sumatriptan-induced memory impairment have been determined in a two-trial recognition Y-maze and passive avoidance tests. Male mice weighing 25-30 g were divided into several groups randomly. In Y-maze test, effects of lithium (1,5,10,20,40,80 mg/kg) and sumatriptan (1,5,10 mg/kg) were assessed on memory acquisition, then lithium (0.1,1,10 mg/kg) and sumatriptan (1,10 mg/kg) were studied in passive avoidance test. Effects of lithium (1mg/kg) on sumatriptan (10 mg/kg)-induced memory impairment were studied in both of tests. The present study demonstrated that sumatriptan impaired memory in Y-maze and passive avoidance tests (P 0.05), but significantly reversed sumatriptan-induced memory impairment in Y-maze and passive avoidance tests (P<0.001, P<0.05, respectively). It is concluded that lithium reverses the sumatriptan-induced memory impairment probably through 5-HT1B/1D receptors antagonism. Keywords: 5-HT1B/1D; Lithium; Mice; Spatial recognition memory; Sumatriptan.

Is it bad to take sumatriptan 3 days in a row?

divalproex (Depakote)erenumab ( Aimovig )fremanezumab ( Ajovy ) gabapentin (Neurontin) propranolol (Inderal) topiramate ( Topamax ) verapamil (Calan SR, Verelan)

If you have troublesome nausea with your migraine headaches, your doctor may also prescribe antinausea medication to take with sumatriptan oral tablets. Examples include:

metoclopramide (Reglan)ondansetron (Zofran) promethazine

Finally, if the recommended dose of sumatriptan does not relieve your symptoms, your doctor may recommend taking certain other pain-relieving medications. Examples include:

over-the-counter pain relievers, such as:

acetaminophen (Tylenol)

acetaminophen/aspirin/caffeine (Excedrin Migraine)

aspirin

ibuprofen (Advil, Motrin)

naproxen (Aleve)

prescription pain relievers, such as:

acetaminophen/caffeine/dihydrocodeine (Trezix)

acetaminophen/codeine (Tylenol with codeine)

diclofenac

ketorolac

tramadol

Can I take sumatriptan 2 days in a row?

Why can you only take sumatriptan twice a week?

Sumatriptan – for migraine and cluster headaches – Imigran

table>

Many migraine attacks occur for no apparent reason, but for some people there may be things which trigger an attack, like certain foods or drinks. consist of attacks of severe one-sided pain in the head. Typically, a number of attacks will occur over several weeks and then pass. It may then be weeks, months or years until the next cluster of headaches develops.

There are two strengths of sumatriptan tablet available (50 mg and 100 mg), one strength of injection (6 mg/0.5 ml) and one strength of nasal spray (10 mg/actuation).
The injection is usually prescribed for people with cluster headaches, whereas the injection, spray or tablets may be prescribed for people with migraines.

Common sumatriptan side-effects	What can I do if I experience this?
Feeling dizzy, sleepy, or tired	If this happens, do not drive and do not use tools or machines
Feeling sick (nausea) or being sick (vomiting)	Stick to simple foods
Feelings ot tightness or heaviness, particularly in the throat or chest	If the pain is intense, do not take any further doses and speak with your doctor about it as soon as possible
Tingling feelings, feeling flushed, feeling warm or cold, aches and pains, increased blood pressure, feeling short of breath	If any of these become troublesome, speak with your doctor
Unpleasant or bitter taste (if using the nasal spray), and injection site reactions (if using the injection)	These should soon pass

If you experience any other symptoms that you think may be due to the medicine, speak with your doctor or pharmacist for advice.

Keep all medicines out of the reach and sight of children.Store in a cool, dry place, away from direct heat and light.

Sumatriptan – for migraine and cluster headaches – Imigran

Can you sleep after taking sumatriptan?

– Sumatriptan oral tablet may cause drowsiness. It may also cause other side effects.

Gaspar Aparicio