What is cinnamon moonshine?
FREE GROUND SHIPPING WITH PURCHASE OF ANY 6 SPIRITS! This product can only be shipped to the following states/locations: Kentucky, Washington D.C., North Dakota, and Alaska. The adult version of a cinnamon hard candy, our Cinnamon moonshine is infused with cinnamon sticks and sweetened with a touch of sugar, but watch out! It goes down smooth as molasses, yet packs a punch like Ali.60 proof.
What are the ingredients to moonshine?
How is Moonshine Made? – The traditional ingredients for moonshine are corn and sugar, and during fermentation, the sugar produces ethanol, which makes hooch or moonshine. During distillation, alcohol separates from the mash. Unlike other liquors such as whiskey or bourbon, moonshine is unaged, which produces a distilled spirit with high alcohol content.
The stereotype of moonshiners centers around how “country folk” distill and transport their potables in jugs marked “XXX” during the night to avoid being detected. But having access to commercially produced all-copper moonshine stills on the internet has made moonshine distillation less risky in the modern era.
But for a great drink, here is the recipe:
What does cinnamon do in alcohol?
How does cinnamon extract protect against alcohol-induced steatosis?. – Previous studies have indicated that intestinal bacterial overgrowth, increased intestinal translocation of bacterial endotoxin, the subsequent activation of Kupffer cells (e.g. formation of reactive oxygen species), and release of TNF α play a key role in the development of acute and chronic alcohol-induced liver damage,
Furthermore, results obtained in rodent models of ALD suggest that therapies interfering with the intestinal bacterial overgrowth and Kupffer cell activation (e.g. antibiotics and antioxidants) may protect against ALD. Results of other groups such as Azumi et al. ( 16) using water-soluble cinnamon extracts suggest that some cinnamon extracts might possess an endotoxin-binding capacity; however, the alcoholic cinnamon extract at concentrations used in the present study did not posses any endotoxin-binding capacity (Supplemental Table 1).
Because the results of Anderson et al. ( 20) and our own experiments indicate that cinnamon extract derived from water-based or alcoholic cinnamon bark may posses a marked antioxidative capacity (see Supplemental Table 2), we determined the effect of cinnamon extract on the alcohol-dependent induction of iNOS in livers of mice.
Indeed, treatment with cinnamon extract almost completely protected mice from acute ethanol-induced induction of hepatic iNOS; however, we also found an almost complete protection of mice against acute ethanol-induced expression of hepatic MyD88, whereas TLR4 expression was not affected regardless of treatment.
Taken together, our data obtained in vivo in mouse liver suggest that cinnamon extract may block the ethanol-induced activation of hepatic Kupffer cells. To further exploit the concept that cinnamon extract might protect livers from acute alcohol-induced steatosis through blocking the endotoxin-induced expression of the MyD88 and thereby blocking the MyD88 signaling cascade in Kupffer cells, we determined the expression of TLR4, MyD88, TNF α, and iNOS as well as iNOS protein levels and the release of nitrite in LPS-treated RAW 264.7 macrophages, a model of hepatic Kupffer cells.
Similar to the results obtained in vivo, expression of TLR4 was not affected by LPS and/or cinnamon extract in RAW 264.7 macrophages. In contrast, MyD88 and all other parameters were significantly decreased in a dose-dependent way in LPS-challenged cells concomitantly treated with cinnamon extract. Because the activation of the transcription factor nuclear factor- κ B (NF κ B) is critical for TNF α production and NF κ B can be regulated redox-sensitive, we also determined phosphor-I κ B α levels in RAW 264.7 cells.
Consistent with our results found for MyD88, TNF α, and iNOS expression as well as nitrite release, the LPS-induced increase of phosphor-I κ B α levels was significantly blocked in cells concomitantly treated with cinnamon extract while stimulated with LPS.
Taken together, these data show that the protective effect of alcohol extract of cinnamon bark under the conditions used in our experiments may result from an inhibition of the expression of MyD88, probably through mechanisms involving an interaction of cinnamon extract with transcription factors involved in the LPS-induced induction of MyD88 and the subsequent formation of reactive oxygen species and blockage of the NF κ B activation; however, the exact mechanisms involved and the components of cinnamon bark responsible for the inhibitory effects on MyD88 mRNA expression remain to be determined.
Our results further indicate that the extraction methods used to obtain the cinnamon extract (e.g. water vs. ethanol) may markedly influence its effects. These results do not preclude that alcohol extracts obtained from cinnamon bark may also exert protection through antioxidative effect or other mechanisms.
- In summary, the results of the present study suggest that alcoholic extracts of cinnamon bark protect against acute alcohol-induced liver steatosis by attenuating the alcohol-dependent induction of MyD88 and the subsequent formation of reactive oxygen species and induction of TNF α,
- Furthermore, these results add further weight to the concept that pharmacological or nutritive supplementation substances interfering with the activation of Kupffer cells have the potential to protect the liver from alcohol-induced damage.
Although future studies will be needed to identify the compound(s) responsible for the protective effects of alcoholic cinnamon extract and to further explore the effects of the cinnamon extract in humans, our results suggest that alcohol extracts of cinnamon may be useful therapeutically for the treatment of diseases associated with an activation of MyD88.
How long does cinnamon moonshine last?
‘How long will a jar keep unopened.’ Different flavors will have different life spans. Generally they will last two years unopened and about six months after opening. They will generally last longer if you store them in the fridge after opening as well.
Who makes cinnamon moonshine?
Produced by the Ole Smoky Distillery, located in the Great Smoky Mountains, this moonshine is made using a unique blend of cinnamon and spices. The result is a sweet and spicy spirit with a smooth and mellow finish that is perfect for sipping on its own or mixing in cocktails.